articol osteosarcom
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7/23/2019 articol osteosarcom
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PE-206 - MANDIBULAR OSTEOSARCOMA: CASE
REPORT. JULYANNA FILGUEIRAS GONALVES DEFARIAS, DANIELA PITA DE MELO, POLLIANNA MUNIZALVES, CASSIANO FRANCISCO WEEGE NONAKA,GUSTAVO PINA GODOY, PATRCIA MEIRA BENTO,DALIANA QUEIROGA DE CASTRO GOMES. UNI-VERSIDADE ESTADUAL DA PARABA.
Osteosarcoma is an aggressive malignancy that originates
from primitive bone-forming mesenchymal cells and is charac-
terized by osteoid matrix production. Osteosarcomas are rela-
tively rare in the head and neck region. Approximately 5% of all
osteosarcomas occur in the jaws. Woman, 40, had a chief
complaint of strong pain and swelling in the mandible. Her
medical history revealed breast cancer. Intraoral examination
showed a lesion localized in the alveolar ridge between the third
molar and the second premolar on the right side of the mandible.
Panoramic radiograph and computed tomography revealed
alteration in the trabecular bone with no well-dened bound-
aries. Microscopically, intense cell proliferation and osteoid
matrix deposition were observed. The diagnosis was consistent
with osteosarcoma of metastatic breast cancer origin. Osteosar-
comas of the jaws are rare entities, but can evolve rapidly and
aggressively. Therefore knowledge of this lesion is vital to
correctly diagnose and treat patients.
PE-207 - MASTICATORY SPACE TUMOR: SCHWAN-
NOMA WITH PSEUDOCYSTIC CHANGES. ANDREZAVERUSKA LIRA CORREIA, LUCIANO PADILHA DOSSANTOS, JUREMA FREIRE LISBOA DE CASTRO, FLVIAMARIA DE MORAES RAMOS-PEREZ, FELIPE PAIVAFONSECA, OSLEI PAES DE ALMEIDA, DANYEL ELIAS DACRUZ PEREZ. FEDERAL UNIVERSITY OF PERNAM-BUCO; STATE UNIVERSITY OF CAMPINAS.
Schwannomas are benign neoplasms that arise from
Schwann cells. About 45% are located in the head and neckregion. The presence of pseudocystic areas is uncommon. A
case of schwannoma with pseudocystic areas was reported.
Woman, 57, was referred for diagnosis of a swelling located in
the oropharynx. Computed tomography revealed a well-dened
hypodense image within the medial and lateral pterygoid
muscles, measuring 4.0 cm in length. The lesion was excised
under local anesthesia. Microscopically, there were hyper-
cellular areas, with frequent nuclear palisading arrangements
(Antoni A pattern), interspersed by less dense reticular areas. A
large pseudocystic area was observed. Tumor cells were posi-
tive for S-100 protein, suggesting the diagnosis of schwan-
noma. In conclusion, schwannomas are well-circumscribed
lesions that may contain pseudocystic areas but carry a good
prognosis.
PE-208 - MELANOMA IN THE ORAL CAVITY: CLINICAL
CASE REPORT. VIVIANE DA SILVA SIQUEIRA, ANELISERIBEIRO PEIXOTO ALENCAR, ANDRESA BORGESSOARES, JOS FERREIRA DE MENEZES FILHO,FABRICIO PASSADOR SANTOS, RAFAEL STELINI. FAC-ULDADE DE ODONTOLOGIA SO LEOPOLDO MANDIC.
Melanoma is rare in the oral cavity, representing 0.2% to
8% of all melanomas. Man, 73, complained of a swelling,
present for the last 2 months, occurring after a dental extraction.
The lesion had been increasing in size. Oral examination
revealed an asymptomatic, exophytic, pigmented lesion,
measuring 5 5 cm, that was accompanied by an unpleasant
odor. An incisional biopsy was performed. Histopathological
examination revealed a fragment of mucosa lined by a stratied
squamous parakeratinized epithelium, showing numerous
irregularly distributed melanocytes, intense nuclear pleomor-
phism, and hyperchromatism. Melanocytic positivity was
demonstrated on immunohistochemical tests for HMB 45, S-
100, and Melan-A. The denitive diagnosis was melanoma. The
patient was referred to a head and neck surgeon for treatment.After investigation, metastatic lung disease was diagnosed. The
treatment of choice was palliative chemotherapy, but the patient
died 2 months after diagnosis.
PE-209 - MELANOTIC NEUROECTODERMAL TUMOR
OF INFANCY: CASE REPORT WITH 1-YEAR FOLLOW-
UP. JULIANA SEO, DANIEL ISAAC SENDYK, MARIACRISTINA ZINDEL DEBONI, DANIEL MARTINS DESOUZA, NORBERTO NOBUO SUGAYA, FABIO DAUMASNUNES. FACULDADE DE ODONTOLOGIA DA UNI-VERSIDADE DE SO PAULO.
Melanotic neuroectodermal tumor of infancy (MNTI) is a
rare, fast-growing tumor with a high recurrence rate. Com-monly it develops in the anterior maxilla of children younger
than age 1 year. Tumor origin is the neural crest. Girl, 2 months,
had an increasingly large area of swelling on the left cheek.
After tomography and biopsy, the diagnosis of MNTI was
established. Histological examination indicated a remarkable
combination of neural, melanocytic, and epithelial cell differ-
entiation. One year after tumor excision, the child has had no
recurrence. Since its rst description, about 260 cases of this
tumor have been reported. Early diagnosis minimized difculties
and risks during treatment and leads to an optimal outcome.
Despite complete surgical excision, careful follow-up is rec-
ommended. Maxillary functional orthopedic care and recon-
struction may be necessary.
PE-210 - MONOSTOTIC FIBROUS DYSPLASIA OF THE
JAW: CASE REPORT WITH 10-YEAR FOLLOW-UP.
SNTIQUE PRISCILA ALVES LUZ, JULIANA BASTOSFIGUEIRA, JSSICA OLIVEIRA MELO SILVA, LAIRARENATA LEMOS SANTOS, VIVIANE ALMEIDASARMENTO, PATRCIA LEITE RIBEIRO LAMBERTI. UNI-VERSIDADE FEDERAL DA BAHIA.
Fibrous dysplasia is an idiopathic benign bro-osseous
lesion in which the normal bone is replaced by brous tissue. The
monostotic form is found in 80% of diagnosed cases. Computed
tomography is the most common imaging method performed to
demonstrate the extent of the lesion in craniofacial bones. Sur-
gical treatment includes reducing the injury to an acceptablemargin, but future development is possible in 25% to 50% of
cases. Woman, 34, was diagnosed with monostotic brous
dysplasia of the jaw. She had been followed up for 10 years
through clinical and imaging surveillance at the School of
Dentistry, Federal University of Bahia.
PE-211 - MUCOEPIDERMOID CARCINOMA IN A
YOUNG PATIENT: CASE REPORT. ANA PAULA CANDIDODOS SANTOS, ANA PATRCIA CARNEIRO GONALVESBEZERRA COELHO, RENATA MENDES MOURA, FABIODAUMAS NUNES, DCIO DOS SANTOS PINTO JR.,ANDREA LUSVARGHI WITZEL, CELSO AUGUSTOLEMOS. FACULDADE DE ODONTOLOGIA DA USP.
ORAL AND MAXILLOFACIAL PATHOLOGY OOOO
e172 Abstracts February 2014
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