Antagonisti selectivi beta 1 adrenergiciAtenolol, metoprolol, acetabutol, esmolol, bisoprolol, nebivolul, betaxololCaract: -medicam cardioselective-pe beta 1 -la doze mari bronhoconstrictie pe beta 2-difera prin t Metoprolol 3-4 ore, atenolol 6 ore, bisoprolol 10-12 ore, betaxolol 15-20 hEfecte farmac: -inhiba apoptoza(moartea celulara) miocardica-bisoprolol, nebivolol, metoprolol succinat=> indicatie ICC -scade TA -cresc toleranta la efort in angina pect -act min la niv pul , metabolic, circ perifIndicatii -propanolol inclusiv la pacientii care au asociat: astm, DZ, arteriopatie -insuf cardiaca bisoprolol, nebivolol, metoprolol succinanAntagonisti beta adrenergici cu activitate simpatica intrinsecaPindolo, acetabutolMod de act: -se fix pe beta adrenergici=> impiedica act catecolamnielor pe ei -stim beta dar nu cu acelasi eficienta ca a catecolaminelorIndicatii: -HTA+ la bolnavii cu DZ -HTA +bradicardie -indicatiile propanololului

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