tematica pentru concursul de admitere … doctorat biologie 2017... · richter g. - 1993 –...
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UNIVERSITATEA ALEXANDRU IOAN CUZA DIN IAI
FACULTATEA DE BIOLOGIE COALA DOCTORAL
TEMATICA PENTRU
CONCURSUL DE ADMITERE
(sesiunea septembrie 2017)
1. Prof. univ. Dr. Maria Magdalena
ZAMFIRACHE Domeniul fundamental de doctorat: BIOLOGIE
Domeniul de doctorat: Biologie (Botanic - fiziologia plantelor)
Direcie general de cercetare pentru doctorat:
(RO)
1) Efecte ale unor factori biotici i abiotici asupra proceselor fiziologice fundamentale la specii
de plante spontane i cultivate.
(ENG)
1) Effects of biotic and abiotic factors on fundamental physiological processes at spontaneous
and cultivated plant species.
BIBLIOGRAFIE MINIMAL (REFERENCES):
1. BURZO I., TOMA S., CRACIUN C., VOICAN V., DOBRESCU A., DELIAN E., 1999
Fiziologia plantelor de cultur. Vol. 1 - Procesele fiziologice din plantele de cultur. Ed. tiina
Chiinu.
2. BURZO I - 2014 Modificrile climatice i efectele asupra plantelor horticole. Ed. Sitech, Craiova.
3. BURZO I. 2015 Stresul abiotic la plantele de cultur. Ed. Elisavaros, Bucureti.
4. BURZO I., AMRIUEI A. - 2016 - Sensibilitatea i reaciile inteligente ale plantelor. Ed.
Elisavaros, Bucureti.
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5. DOBROT C., YAMASHITA M. 1999 Creterea i dezvoltarea plantelor. Casa de editur
Gloria, Cluj-Napoca.
6. DOBROT C. 2012, 2013 Fiziologia plantelor, Vol. 1., Vol. 2. Ed. Risoprint, Cluj-Napoca.
7. DESSAUX Y., HINSINGER PH., LEMANCEAU PH. (Ed.), 2010 Rhizosphere: Achievements
and Challenges. Ed. Springer, Germany.
8. DUHOUX E., MICHEL N., 2004 Biologie vgtale. Ed. Dunod, Paris.
9. DUCA M - 1997 - Sisteme i mecanisme de autoreglare la plante. Secia poligrafie operativ a
USM, Chiinu.
10. DUCA M. 2009 Fiziologie vegetal. Ed. tiina Chiinu.
11. HELLER R., ESNAULT R., LANCE C., 1998 Physiologie vgtale, 1 Nutrition. Ed. Dunod,
Paris.
12. JENIFER W., Mac. ADAM 2009 Structure and function of plants. Ed. Wiley Blackwell.
13. JITREANU C. D.- 2007 Fiziologia plantelor. Ed. Ion Ionescu de la Brad Iai.
14. LTTGE U., KLUGE M., BAUER G. 1992 Botanique - Trait fondamental. Tec. & Doc.
Lavoisier, Paris.
15. RICHTER G. - 1993 Mtabolisme des vgtaux Physiologie et biochimie. Ed. Ramandes,
Lausanne.
16. SCHEEL D., WASTERNACK C. (Ed.) 2002 Plant Signal Transduction. Oxford University
Press.
17. SELOSSE M.- A. 2005 La symbiose. Ed. Vuibert, Paris.
18. TAIZ L., ZEIGER E. 2006 - Plant Physilogy, Sinauer Associates, Inc., Publishers Sunderland,
Massachusetts, USA.
19. TOMA C 2002 - Strategii evolutive n regnul vegetal. Ed. Univ. Al. I. Cuza Iai.
20. TOURTE Y., BORDONNEAU M., HENRY M., TOURTE C. 2005 - Le monde des vgtaux. Ed.
Dounod Paris.
21. ZAMFIRACHE M. M. , TOMA C. 2000 Simbioza n lumea vie. Ed. Univ. Al. I. Cuza Iai.
22. ZAMFIRACHE M. M. 2005 Fiziologie vegetal. Vol. 1. Ed. Azimuth Iai.
2. Prof.univ. Dr. Ctlin TNASE Domeniul fundamental de doctorat: BIOLOGIE
Domeniul de doctorat: Biologie (Botanic)
Direcii generale de cercetare pentru doctorat:
(RO)
MICOLOGIE I FITOPATOLOGIE
a) Biologia i ecologia fungilor
b) Aplicaiile fungilor n biotehnologii
c) Interaciuni biotice
d) Micozele plantelor cultivate
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BOTANIC I VALORIFICAREA SUSTENABIL A FITODIVERSITII
a) Taxonomia, ecologia i conservarea plantelor
b) Habitatele din Romnia
c) Biotehnologia, fitochimia i valorificarea sustenabil a plantelor medicinale
(ENG)
MYCOLOGY AND PHYTOPATHOLOGY
a) Biology and ecology of fungi
b) Fungal applications in biotechnology
c) Biotic interactions
d) The mycosis of crops
BOTANICS AND SUSTAINABLE EXPLOITATIONS OF PHYTODIVERSITY
a) Taxonomy, ecology and conservation of plants
b) Habitats from Romania
c) Biotechnology, phytochemistry and sustainable exploitations of herbs
BIBLIOGRAFIE MINIMAL (REFERENCES):
1. AGRIOS G, 2005. Plant pathology (5-th edition). Elsevier Academic Press.
2. ALEXAN M., BOJOR O., CRCIUN Fl., 1992. Flora medicinal a Romniei. Ed. Ceres, Bucureti,
vol. I i II.
3. CAPASSO F., GACINELLA S.T., GRANDOLINI G., IZZO A.A. 2003. Phytotherapy: a quick
reference to herbal medicine. Berlin, New York, Springer.
4. CARLILE J.M., WATKINSON S.C., GRAHAM W.G., 2001. The Fungi. Academic Press, London
UK.
5. CRISTEA V., GAFTA D., PEDROTTI F., 2004. Fitosociologie. Ed. Presa Universitar Clujean,
Cluj-Napoca.
6. CRISTEA V., 2014. Plante vasculare: diversitate, sistematic, ecologie i importan. Editura Presa
Universitar Clujean.
7. DIX N. J., WEBSTER J., 1995. Fungal Ecology. Chapman & Hall, London.
8. DONI N., PAUC-COMNESCU Mihaela, POPESCU A., MIHILESCU Simona, BIRI I.A.,
2005. Habitatele din Romnia. Ed. Tehnic Silvic, Bucureti.
9. HOBBS C., 1995. Medicinal Mushrooms. An exploration of tradition, healing and culture. Botanica
Press, Summertown, Tennessee.
10. JEFFRIES J. M., 2006. Biodiversity and Conservation (Second edition). Ed. Routledge, Oxford,
UK/New York
11. KAYSER O., QUAX W. J., 2007. Medicinal Plant Biotechnology From Basic Research to
Industrial Application. Ed. Wiley-VCH Verlag, Weinheim.
12. KAVANAGH K., 2005. Fungi. Biology and Applications. John Wiley & Sons, Ltd, England.
13. MITITIUC M., 1994. Fitopatologie. Ed. Universitii Alexandru Ioan Cuza din Iai.
14. POPESCU Gh., 2009. Introducere n Botanica filogenetic. Ed. Sitech, Craiova.
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15. SINGH H., 2006. Mycoremediation. Fungal Bioremediation. John Wiley & Sons, Inc., Hoboken,
New Jersey.
16. SINGH M. P., SINGH B. S., 2002. Plant Biodiversity and Taxonomy. Ed. Daya Publishing House,
New Delhi.
17. ESAN Tatiana Eugenia, TNASE C., 2007. Ciuperci anamorfe fitopatogene. Ed. Universitii din
Bucureti.
18. ESAN Tatiana Eugenia, TNASE C., 2009. Fungi cu aplicaii n agricultur, medicin i
patrimoniu. Ed. Universitii din Bucureti.
19. ESAN Tatiana Eugenia, TNASE C., 2013. Ascomicete fitopatogene (ediia a II-a revzut i
adugit). Editura Universitii din Bucureti.
20. TEFAN N., OPREA A., 2007. Botanic sistematic. Ed. Universitii Alexandru Ioan Cuza din
Iai.
21. TNASE C., ESAN Tatiana Eugenia, 2006. Concepte actuale n taxonomia ciupercilor. Ed. Univ.
Al. I. Cuza Iai.
22. TNASE C., BRSAN C., CHINAN V., COJOCARIU Ana, 2009. Macromicete din Romnia. Ed.
Universitii Alexandru Ioan Cuza din Iai.
3. Prof. univ. Dr. Dumitru COJOCARU
Domeniul fundamental de doctorat: BIOLOGIE
Domeniul de doctorat: Biologie (Biochimie)
Direcii generale de cercetare pentru doctorat:
(RO)
1. Macromolecule informaionale
1.1. Proteine: definiie, clasificare, structura chimic, rol biologic
1.2. Acizi nucleici: definiie, clasificare, structura chimic, rol biologic
1.3. Enzime: definiie, clasificare, structura chimic, cinetica reaciilor enzimatice
2. Metabolismul substanelor i energiei
2.1. Digestia i absorbia glucidelor, lipidelor i proteinelor
2.2. Glicoliza anaerob. 2.3. Ciclul Krebs
2.4. Catena respiratorie. 2.5. Beta-oxidarea acizilor grai
2.6. Ci comune de degradare a aminoacizilor
2.7. Ciclul ureogenetic
2.8. Mecanismele moleculare ale replicrii ADN-ului
2.9. Biosinteza proteinelor. 2.10. Reglarea biosintezei proteice
(ENG)
1. Informational macromolecules
1.1.Proteins: definition, classification, chemical structure, biological role.
1.2. Nucleic acids: definition, classification, chemical structure, biological role.
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1.3. Enzymes: definition, classification, chemical structure, kinetics.
2. Energy and metabolism
2.1. Digestion and absorption of sugars, lipids and proteins.
2.2. Anaerobic glycolysis. 2.3. The Krebs cycle
2.4. The respiratory chain. 2.5. The beta-oxidation of fatty acids
2.6. Common amino-acids catabolic pathways
2.7. The ureogenetic cycle
2.8. Molecular mechanism of DNA replication
2.9. Protein bio-synthesis. 2.10. Regulation of protein synthesis
BIBLIOGRAFIE MINIMAL - (REFERENCES):
1. Artenie, Vl. 1991, Biochimie, Ed. Univ. Al. I. Cuza Iai.
2. Cojocaru, D.C., Mariana Sandu 2004, Biochimia proteinelor i acizilor nucleici, Ed. Pim, Iai.
3. Cojocaru, D. C., Zenovia Olteanu, Elena Ciornea, Lcrmioara Opric, Sabina Ioana Cojocaru
2007, Enzimologie general, Ed. TEHNOPRESS, Iai
4. Dumitru, I. F. 1980, Biochimie, Ed. Did. i Ped., Bucureti.
4. C.S. II Habilitat Dr. Alin Stelian CIOBC
Domeniul fundamental de doctorat: BIOLOGIE
Domeniul de doctorat: Biologie (fiziologie animal)
Direcii generale de cercetare pentru doctorat:
(RO):
a) Modele animale de boli neuropsihiatrice;
b) Relevana stresului oxidativ n unele boli de natur neuropsihiatric, cardiovascular,
digestiv sau metabolic: modele animale i pacieni umani;
c) Alte aspecte de cercetare translaional biomedical: modele animale i pacieni
umani.
d) Oxitocina: importana n boli neuropsihiatrice, implicarea n procesele de nocicepie,
n statusul stresului oxidativ i a funciilor sexuale i dezvoltrii piho-motorii a nou-
nscutului (modele animale), precum i relevana modului de administrare
(intranazal vs. periferic).
(ENG):
a) Animal models of neuropsychiatric disorders;
b) The relevance of oxidative stress in some neuropsychiatric, cardiovascular, digestive
or metabolic diseases: human patients and animal models;
c) Various types of biomedical translational research: human patients and animal
models.
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d) Oxytocin: its importance in neuropsychiatric disorders management, relevance for
the nociceptive processes, oxidative stress modifications and sexual/newborn
development implications (animal models), as well as the importance of the
administration method (intranasal vs. peripheral).
BIBLIOGRAFIE - (REFERENCES):
1. Koho Miyoshi, Yasushi Morimura, Kiyoshi Maeda, Neuropsychiatric Disorders, Springer, 2010.
2. Hefco V., Fiziologie experimentala.Vol.I-III , Ed.Univ.Iai 1975-1977.
3. Hefco V.P., Fiziologia animalelor si a omului.Ed.Did.Ped.Bucureti, 1997.
4. Halliwell B, Gutteridge JMC, Free radical in biology and medicine, 4th edn. Oxford Univ Press,
New York, 2007.
5. Melnic, B., Hefco V., Crivoi A., Fiziologia omului si animalelor.Ed.t,Chiinu, 1993.
6. Strungaru Gr., Pop M., Hefco V., Fiziologia animal. Ed.Did.Ped.Bucureti, 1983
7. Webster RA. Neurotransmitters, Drugs and Brain Function. John Wiley & Sons, 2002
8. Guastella AJ, Hickie IB. Oxytocin Treatment, Circuitry, and Autism: A Critical Review of the
Literature Placing Oxytocin Into the Autism Context. Biol Psychiatry. 2016 Feb 1;79(3):234-42.
9. Guastella AJ, Ward PB, Hickie IB, Shahrestani S, Hodge MA, Scott EM, Langdon R. A single dose
of oxytocin nasal spray improves higher-order social cognition in schizophrenia. Schizophr Res.
2015 Nov;168(3):628-33.
5. Prof.univ. Dr. Habil. Marius TEFAN Domeniul fundamental de doctorat: BIOLOGIE
Domeniul de doctorat: Biologie (Microbiologie)
Direcii generale de cercetare pentru doctorat:
(RO)
MICROBIOLOGIE GENERAL
1. Interaciuni plante-microorganisme la nivelul rizosferei
2. Studiul efectelor antimicrobiene ale unor compui naturali i de sintez
3. Microorganismele surse de substane biologic active
BIOTEHNOLOGII MICROBIENE
1. Aplicaii biotehnologice ale unor microorganisme rizosferice cu potenial de stimulare a
creterii plantelor
2. Aplicaii ale unor biomolecule cu proprieti antifungice n protecia plantelor
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(ENG)
GENERAL MICROBIOLOGY
1. Rhizosphere plant-microbial interactions
2. Study of antimicrobial effects of natural and synthetic compounds
3. Microorganisms as potential sources of biologically active substances
MICROBIAL BIOTECHNOLOGY
1. Biotechnological applications of rhizobacteria with plant growth promotion capabilities
2. Applications of some biomolecules with antifungal properties in plant protection
BIBLIOGRAFIE MINIMAL - (REFERENCES):
1. Alcamo, I.E., 2003 - Microbes and society, an introduction to microbiology, Jones and
Bartlett Publishers, Boston.
2. Dunca, S., Ailiesei, O., Nimian, E., tefan, M., 2005 - Elemente de microbiologie, vol. I,
Ed. Junimea, Iai.
3. Jurcoane, ., 2000 - Biotehnologii fundamente, bioreactoare, enzime, Ed. Tehnic,
Bucureti.
4. Singh, U.S., Kapoor, K., 2010 - Microbial Biotechnology, Oxford Book Company.
5. tefan, M., 2014 - Applied microbiology: from plant growth promotion to new
neuroprotective drugs, Ed. Universitii Alexandru Ioan Cuza din Iai, ISBN 978-606-714-
091-0, p. 213.
6. tefan M., 2008 - Biologia microorganismelor rizosferice - aplicaii biotehnologice, Ed.
Tehnopress Iai, ISBN 973-702-597-5, p. 369.
7. Zarnea, G., 1983 - Tratat de microbiologie general, vol. I, Ed. Academiei R.S.R.,
Bucureti
8. Zarnea, G., 1994 - Tratat de microbiologie general, vol. V, Ed. Academiei Romne,
Bucureti.
6. Prof. Dr. Habil. Lucian HRICU
Domeniul fundamental de doctorat: BIOLOGIE
Domeniul de doctorat: Biologie (fiziologie animal)
Direcie general de cercetare pentru doctorat:
(RO)
1. Rolul unor zone nervoase i neurotransmitori n reglarea proceselor nvrii i memoriei
utiliznd modele experimentale animale
http://www.sciencedirect.com/science/article/pii/S0168165699000589
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2. Hormonii, creierul i procesele cognitive. Studii pe modele experimentale animale.
3. Evaluarea biologic complex a unor extracte de origine vegetal selecionate ca remedii
terapeutice de elecie pe model experimental animal.
4. Evaluarea biologic complex a aciunii unor peptide amilolitice utiliznd modele experimentale
animale
(ENG)
1. Role of the nervous areas and neurotransmitters in regulating of learning and memory processes
using experimental animal models
2. Hormones, brain, and cognitive processes. Studies on experimental animal models.
3. Complex biological evaluation of selected plant extracts used as therapeutic remedies on animal
experimental model
4. Complex biological evaluation of the action of some amyloid peptides using experimental animal
models
BIBLIOGRAFIE MINIMAL (REFERENCES):
1. Nou,edem, J.A.K., Djeussi, D.E., Hritcu L., Mihan, M., Kuete, V., 2017. Chapterr 20 Lactuca
sativa, Medicinal Spices and Vegetables from Africa. Academic Press, Elsevier, pp. 437-449.
2. Hritcu L., Cioanca O, 2016, Prevalence of Use of Herbal Medicines and Complementary and
Alternative Medicine in Europe, in: Grosso, C. (Ed.) Herbal Medicine in Depression: Traditional
Medicine to Innovative Drug Delivery. Springer International Publishing, Cham, pp. 135-181.
3. Hritcu L. 2011, Neurofiziologie Rolul unor neurotransmitori i zone nervoase n modularea
proceselor cognitive i imunitare, Editura Universitii Alexandru Ioan Cuza din Iai, ISBN
978-973-640-670-6, 231 pagini.
4. Hritcu L. 2012, Fiziologie animal experimental, , Editura Universitii Alexandru Ioan
Cuza din Iai, ISBN: 978-973-703-849-4, 130 pagini.
5. Hritcu L., Hefco V. 2007, Elemente de fiziologia animalelor si a omului funcii de relaie. Editura
PIM (acreditat CNCSIS, cod CNCSIS 66), Iai, ISBN 978-973-716-695-1, 301 pagini.
6. Hritcu L. 2010, Fiziologia animalelor i a omului sistemul endocrin, reproducerea i funciile de
nutriie. Editura Tehnopress (acreditat CNCSIS, cod CNCSIS 89), Iai, ISBN 978-973-702-580-
7, 392 pagini.
7. Hefco V. 1997, Fiziologia animalelor i a omului, Editura Didactic i Pedagogic, Bucuresti, 633
pagini.
8. Kandel E, Schwartz J, Jessell T, 2000, Principles of Neural Science, Fourth Edition, McGrawHill.
9. Kuete, V., 2017, Medicinal Spices and Vegetables from Africa. Academic Press, Elsevier, 669
pagini.
10. Purves D, Augustine G, Fitzpatrick D, Hall W, LaMantia AS, White L 2004, Neuroscience, Sinauer.
11. Webster RA 2001, Neurotransmitters, Drugs and Brain Function, Wiley
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7. Conf.univ. Dr. Habil. Mircea
Dan MITROIU
Domeniul fundamental de doctorat: BIOLOGIE
Domeniul de doctorat: Biologie (zoologie)
Direcie general de cercetare pentru doctorat:
(RO)
1) Sistematica i ecologia viespilor parazitoide (Insecta: Hymenoptera)
(ENG)
1) Systematics and ecology of parasitoid wasps (Insecta: Hymenoptera)
BIBLIOGRAFIE MINIMAL (REFERENCES):
1. Gauld, I. & Bolton, B., 1988. The Hymenoptera. Oxford University Press, New York.
2. Goulet, H. & Huber, J.T. (eds), 1993. Hymenoptera of the World: an Identification Guide to
Families. Research Branch, Agriculture Canada.
3. Jervis, M. & Kidd, N. (eds), 1996. Insect Natural Enemies. Practical approaches to their study and
evaluation. Chapman & Hall.
4. Noyes, J.S., 1982. Collecting and preserving chalcid wasps (Hymenoptera: Chalcidoidea). Journal
of Natural History 16: 315-334.
5. Lemey, P., Salemi, M. & Vandamme, A.-M. (eds), 2009. The Phylogenetic Handbook. A Practical
Approach to Phylogenetic Analysis and Hypothesis Testing. Cambridge University Press.
6. Quicke, D.L.J., 1997. Parasitic Wasps. Chapman & Hall, London, UK.
7. Wheeler, W.C., 2012. Systematics: A Course of Lectures. Wiley-Blackwell.
8. Wiley, E.O., Siegel-Causey, D., Brooks, D.R. & Funk, V.A., 1991. The Complete Cladist. A Primer
of Phylogenetic Proceedures. The University of Kansas Museum of Natural History, Special
Publications 19.
9. Winston, J.E., 1999. Describing Species. Practical Taxonomic Procedure for Biologists. Columbia
University Press, New York.
8. Conf.univ. Dr. Habil. Drago
Lucian GORGAN
Domeniul fundamental de doctorat: BIOLOGIE
Domeniul de doctorat: Biologie (Biologie molecular Genetic general i molecular)
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Direcie general de cercetare pentru doctorat:
(RO)
Expresie genic i cuantificarea expresiei genice n diferite condiii experimentale:
1. Studii interdisciplinare privind inducerea apoptozei i cuantificarea expresiei markerilor
apoptotici n culturi celulare tumoarale expuse unor ageni fizici sau chimici.
2. Cuantificarea a diferii markeri moleculari cu implicaii n citotoxicitate, genotoxicitate i
ecotoxicitate.
3. Cuantificarea expresiei a diferite gene implicate n patologii dobndite sau motenite.
Filogenie i filogeografie molecular, Genetic populaional i conservativ, Diversitate
1. Studii de filogenie molecular pentru identificarea originii i timpului de divergen a diferite
grupe de organisme, istoria evolutiv a speciilor n corelaie cu evenimentele globale, gradul de
nrudire, procesele de hibridizare intra i interspecific, modificri majore n procesele evolutive.
2. Evaluarea diversitii genetice a speciilor vulnerabile sau periclitate, pentru identificarea unor
soluii de restaurare i conservare a echilibrului populaional i prevenirea proceselor de
consangvinizare.
3. Studiul speciilor invazive, estimarea diversitii intra i inter-populaionale, identificarea
arealelor de origine i a mecanismelor de invazivitate, a timpului de colonizare i a potenialului
de colonizare a noi areale.
4. Studiul interdisciplinar al populaiilor umane vechi, prin identificarea haplogrupurilor specifice,
a originii, diversitii i migraiilor.
(ENG)
Quantification of genes expression and gene expression profiling
1. Interdisciplinary studies for apoptosis induction and quantification of the apoptotic markers in
tumor cell lines exposed to physical or chemical agents.
2. Quantification of various cytotoxicity, genotoxicity and ecotoxicity molecular markers.
3. Quantification of different genes expression involved in induced or inherited pathologies.
Molecular Phylogeny and Phylogeography, Populational and conservative genetics, Diversity
1. Molecular phylogenetic studies allowing based on the DNA sequences analysis, to identify
common origin and time of divergence for different groups of organisms, the species
evolutionary history in correlation with global events, the degree of kinship, intra and inter
specific hybridization processes, significant changes in the evolutionary processes.
2. Evaluation of genetic diversity on vulnerable or endangered species, to identify viable solutions
to restore and preserve the populations balance and avoid the inbreeding processes.
3. The study of invasive species, the estimation of intra- and inter population diversity, the
identification of the origin areas and mechanisms invasiveness, of the colonization time and the
potential of new areas colonization.
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4. The study of ancient human populations, targeting the specific haplogroups, origin, genetic
diversity and migrations.
BIBLIOGRAFIE MINIMAL (REFERENCES):
1. BRA I., CMPEANU M. M., 2003 Genetica, Editura Corson, 233p.
2. BEEBEE T., ROWE G., 2005 An introduction to Molecular Ecology 335 p.
3. BIASSONI R., RASO A., 2014 Quantitative Real-Time PCR, Methods in Molecular Biology 1160,
Springer, ISSN 1064-3745, ISSN 1940-6029, 233p.
4. GEORGESCU S. E., DUDU A., COSTACHE M., 2016 Tehnici de biologie molecular, Editura Univ.
Bucureti, 978-606-16-0729-7, 250p.
5. GORGAN D. L., 2007 Filogenie Molecular n cadrul genurilor Cyprinus i Carassius, Editura
Universitii Al. I. Cuza Iai, 400 p., ISBN 978-973-703-209-6.
6. GORGAN D. L., 2008 Introducere n studiul filogeniei i filogeografiei moleculare, 187 p., Editura
Bioflux, Cluj-Napoca. Online, ISBN 978-973-88929-9-6
7. LESK M. A, 2007 Introduction to genomics, Oxford University Press, 405p.
8. MIHAN M., TEFAN M., OLTEANU Z., 2013 Biologie molecular: metode experimentale,
Editura Universitii Al. I. Cuza, ISBN 978-973-703-816-6, 360p.
9. NEI M., KUMAR S., 2000 Molecular evolution and phylogenetics, Oxford University Press, 333p.
10. TEVFIK D. M., 2006 Real-time PCR, Taylor & Francis Group, 362p.
9. Conf.univ. Dr. Habil. Marius MIHAN
Domeniul fundamental de doctorat: BIOLOGIE
Domeniul de doctorat: Biologie (biochimie i biologie molecular)
Direcie general de cercetare pentru doctorat:
(RO)
1) Caracterizarea complet a ciilor catabolice codificate de megaplasmidul pAO1 din
Arthrobacter nicotinovorans din punct de vedere al originii, evoluiei, organizrii moleculare i
aplicailor biotehnologice.
(ENG)
1) Origin, evolution and biotechnological applications of the catabolic pathways encoded
by the pAO1 megaplasmid of Arthrobacter nicotinovorans.
BIBLIOGRAFIE MINIMAL - (REFERENCES):
1. Igloi, G. L., & Brandsch, R. (2003). Sequence of the 165-kilobase catabolic plasmid pAO1 from
Arthrobacter nicotinovorans and identification of a pAO1-dependent nicotine uptake system. J
Bacteriol, 185(6), 19761986. http://view.ncbi.nlm.nih.gov/pubmed/12618462
http://view.ncbi.nlm.nih.gov/pubmed/12618462
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2. Ganas, P., Igloi, G. L., & Brandsch, R. (2009). The Megaplasmid pAO1 of Arthrobacter
Nicotinovorans and Nicotine Catabolism. In E. Schwartz (Ed.), Microbial Megaplasmids (Vol. 11,
pp. 271282). Berlin, Heidelberg: Springer Berlin Heidelberg. http://doi.org/10.1007/978-3-540-
85467-8
3. Mihan, M., & Brandsch, R. (2016). A predicted T4 secretion system and conserved DNA-repeats
identified in a subset of related Arthrobacter plasmids. Microbiological Research, 191, 3237.
http://doi.org/10.1016/j.micres.2016.05.008
4. Mihan, M. (2015). Bioinformatics-based molecular classification of Arthrobacter plasmids.
Cellular & Molecular Biology Letters, 20(4), 612615. http://doi.org/10.1515/cmble-2015-0036
5. Mihasan, M., & Brandsch, R. (2013). pAO1 of Arthrobacter nicotinovorans and the spread of
catabolic traits by horizontal gene transfer in gram-positive soil bacteria. Journal of Molecular
Evolution, 77(12), 2230. http://doi.org/10.1007/s00239-013-9576-x
6. Liu, J., Ma, G., Chen, T., Hou, Y., Yang, S., Zhang, K.-Q., & Yang, J. (2015). Nicotine-degrading
microorganisms and their potential applications. Applied Microbiology and Biotechnology, 99(9),
37753785. http://doi.org/10.1007/s00253-015-6525-1
7. Gurusamy, R., & Natarajan, S. (2013). Current status on biochemistry and molecular biology of
microbial degradation of nicotine. TheScientificWorldJournal, 2013(Article ID 125385), 125385.
http://doi.org/10.1155/2013/125385
8. Brandsch, R. (2006). Microbiology and biochemistry of nicotine degradation. Appl Microbiol
Biotechnol, 69(5), 493498. http://doi.org/10.1007/s00253-005-0226
9. Mihasan, M., Stefan, M., Hritcu, L., Artenie, V., & Brandsch, R. (2013). Evidence of a plasmid-
encoded oxidative xylose-catabolic pathway in Arthrobacter nicotinovorans pAO1. Research in
Microbiology, 164(1), 2230. http://doi.org/10.1016/j.resmic.2012.10.003
10. Johnsen, U., Dambeck, M., Zaiss, H., Fuhrer, T., Soppa, J., Sauer, U., & Schnheit, P. (2009). d-
Xylose Degradation Pathway in the Halophilic Archaeon Haloferax volcanii . Journal of Biological
Chemistry , 284(40), 2729027303. http://doi.org/10.1074/jbc.M109.003814
11. Aristidou, A., & Penttil, M. (2000). Metabolic engineering applications to renewable resource
utilization. Current Opinion in Biotechnology, 11(2), 187198. Retrieved from
http://www.sciencedirect.com/science/article/pii/S0958166900000859
12. Taly, A., Corringer, P.-J., Guedin, D., Lestage, P., & Changeux, J.-P. (2009). Nicotinic receptors:
allosteric transitions and therapeutic targets in the nervous system. Nat Rev Drug Discov, 8(9), 733
750. Retrieved from http://dx.doi.org/10.1038/nrd2927
13. Posadas, I., Lpez-Hernndez, B., & Cea, V. (2013). Nicotinic receptors in neurodegeneration.
Current Neuropharmacology, 11(3), 298314. http://doi.org/10.2174/1570159X11311030005
14. Parri, H. R., Hernandez, C. M., & Dineley, K. T. (2011). Research update: Alpha7 nicotinic
acetylcholine receptor mechanisms in Alzheimers disease. Biochemical Pharmacology, 82(8), 931
42. http://doi.org/10.1016/j.bcp.2011.06.039
15. Mihasan, M., Capatina, L., Neagu, E., Stefan, M., & Hritcu, L. (2013). In-silico identification of 6-
hydroxy-L-nicotine as a novel neuroprotective drug. Romanian Biotechnological Letters, 18(3),
83338340.
http://doi.org/10.1007/978-3-540-85467-8http://doi.org/10.1007/978-3-540-85467-8http://doi.org/10.1016/j.micres.2016.05.008http://doi.org/10.1515/cmble-2015-0036http://doi.org/10.1007/s00239-013-9576-xhttp://doi.org/10.1007/s00253-015-6525-1http://doi.org/10.1155/2013/125385http://doi.org/10.1007/s00253-005-0226http://doi.org/10.1016/j.resmic.2012.10.003http://doi.org/10.1074/jbc.M109.003814http://www.sciencedirect.com/science/article/pii/S0958166900000859http://dx.doi.org/10.1038/nrd2927http://doi.org/10.2174/1570159X11311030005http://doi.org/10.1016/j.bcp.2011.06.039
-
13
16. Hritcu, L., Stefan, M., Brandsch, R., & Mihasan, M. (2015). Enhanced behavioral response by
decreasing brain oxidative stress to 6-hydroxy-l-nicotine in Alzheimers disease rat model.
Neuroscience Letters, 591, 4147. http://doi.org/10.1016/j.neulet.2015.02.014
17. Hritcu, L., Ionita, R., Motei, D. E., Babii, C., Stefan, M., & Mihasan, M. (2017). Nicotine versus
6-hydroxy-l-nicotine against chlorisondamine induced memory impairment and oxidative stress
in the rat hippocampus. Biomedicine & Pharmacotherapy, 86, 102108.
http://doi.org/10.1016/j.biopha.2016.12.008
DIRECTOR EXECUTIV AL
COLII DOCTORALE,
Prof.univ. Dr. Abilitat Marius TEFAN
DECAN,
Conf.univ. Dr. Lcrmioara Carmen IVNESCU
http://doi.org/10.1016/j.neulet.2015.02.014http://doi.org/10.1016/j.biopha.2016.12.008