sarcoidosis

Atlas of Renal Pathology

From theMedical PAddress a

TN 37232.Am J Kid� 2001 b0272-638http://dx.d

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Sarcoidosis

Agnes Fogo, MD

The AJKD Atlas of Renal Pathology presents a compilation of figures on a specific pathologic entity. You

may download the figures to create your own personal, non-commercial library of images or to create slides for

teaching purposes.

Department of Pathology, Vanderbilt University Medicalhotographer: Brent Weedman.uthor queries to Agnes Fogo, MD, Department of PathologE-mail: Agnes.Fogo@vanderbilt.eduney Dis. 37(2):E12-E13.y the National Kidney Foundation, Inc. Published by Else6/$36.00oi.org/10.1053/S0272-6386(13)90037-8

Fig 1. Renal sarcoidosis is manifest by multiple sharply delin-eated non-necrotizing granulomas with frequent epithelioid-type multinucleated giant cells with accompanying interstitialfibrosis and lymphoplasmacytic interstitial infiltrate, as illustratedhere. (Jones’ Silver Stain, original magnification 3100).

Fig 2. The well delineated non-necrotizing granulomas typicalof sarcoidosis are illustrated here, with adjacent tubulointerstitialfibrosis. Giant cells are evident. (Jones Silver Stain, originalmagnification 3200).

Center, Nashville, TN.

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Am J Kidney Dis. 2001;37(2):E12-E13

Sarcoidosis

Am J Kidney Dis. 2001;37(2):E12-E13

Fig 3. The large giant cells comprising the non-necrotizinggranulomas typical of renal sarcoidosis are evident in this bi-opsy, with surrounding lymphoplasmacytic interstitial infiltrateand early tubulointerstitial fibrosis. (Jones Silver Stain, originalmagnification 3200).

Fig 4. A well-delineated granuloma is seen surrounding anintact glomerulus in this case of renal sarcoidosis. There arenumerous giant cells and surrounding lymphocytes and plasmacells with early interstitial fibrosis. (Hematoxylin and Eosin, orig-inal magnification 3200).

Fig 5. The multinucleated giant cell typical of sarcoidosis isshown under high magnification in this biopsy. (Periodic AcidSchiff, original magnification 3400).

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